Tuesday, October 16, 2012

Vegan pasta recipes for National Pasta Day | Vegan

According to TheNibble.com, October 17 is National Pasta Day, giving you a carb-heavy chance to dig your fork into a pasta-centric plate of comfort food. It?s the perfect time to think outside your usual?spaghetti box and make a new pasta recipe. Here are our top vegan pasta picks.

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Vegan pasta recipes

Pasta sauce recipes

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Source: http://vegan.sheknows.com/2012/10/15/vegan-pasta-recipes-for-national-pasta-day/

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Monday, October 15, 2012

An Interview with HELLBOUND?'s Screenwriter Kevin Miller ...

Vancouver Canada News An Interview with HELLBOUND??s Screenwriter Kevin Miller

Vancouver-based screenwriter Kevin Miller (No Intelligence Allowed, with Ben Stein; Sex+Money, spOILed, With God On Our Side) is back with HELLBOUND?, a whole new documentary that explores today?s highly contentious debate over the Christian doctrine of hell.

HELLBOUND? features interviews with an eclectic group of authors, theologians, pastors, social commentators, musicians, exorcists and other high profile participants in the debate.

?Throughout history, Christians have disagreed about pretty much everything,? says Miller. ?With every debate, particular doctrines become a litmus test to determine ?insiders? and ?outsiders.? That?s certainly the case right now regarding the doctrine of hell. HELLBOUND? is my attempt to get to the bottom of the current debate, to find out why challenges to the traditional ?fire and brimstone view? are so contentious and to discover the implications of this dispute for Christians as well as those watching from a distance.?

Miller has no illusions about the controversy this film might cause. ?No matter what you believe about hell, this film is definitely going to push your buttons. But I see that as a healthy thing. Rather than just stir people up though, I hope HELLBOUND? will provoke informed discussion and get people to take a second look at the impact their religious beliefs have on the world at large.?

I had the chance to speak with Kevin Miller to find out more about HELLBOUND?

Felix: Tell us about HELLBOUND?: what inspired you to make this film?

Kevin: Hellbound? is a feature-length documentary that takes a critical look at the traditional Christian doctrine of hell as a place of eternal torment for the wicked. Far from an abstract theological discussion, the film seeks to understand why Christians who challenge the establishment view get into so much hot water, and how our view of hell affects the kind of world we create.

I was inspired to make the film back in the fall of 2008 when I edited a book called Her Gates Will Never Be Shut: Hope, Hell and the New Jerusalem by Abbotsford author Brad Jersak. That experience opened me up to the fascinating conversation the church has been having about this issue over the past two millennia. Some people would have you believe that the Bible teaches one and only one thing about hell, and that the church has been united around this view from the beginning. This is a total misrepresentation of church history. The fact is, there has always been three main interpretations of hell: 1) Infernalism, eternal torment for the wicked, 2) Annihilationism, the idea that the wicked won?t be punished forever but rather extinguished for eternity and 3) Universalism, the idea that all people will ultimately be reconciled to God?even though some or all of us will have to ?go through hell? to get there. Clearly, at some point in history Infernalism became the dominant view within the Western Church. But a growing number of Christians are questioning whether that pride of place is deserved. Hellbound? documents this debate to see if a case can be made for a form of Christianity that doesn?t include hell?at least not in the way hell is popularly conceived.

Felix: Are you a religious person yourself? Is there a message behind the film?

Kevin: Yes, I would consider myself a Christian. However, whenever I take on that label I feel an increasing need to qualify it somehow, because the word ?Christian? is like a suitcase?you can pack anything into it you like. So I will say this: To me the term ?Christian? doesn?t mean being part of an exclusivist tribe. Rather, it means emulating the life and teachings of Jesus. The core of that is loving God, loving my neighbor?and my enemy?as myself, and a complete abdication of violence.

In terms of the film?s message, I would say it?s a call away from a rigid, fear-driven form of religion, because I think this form of belief?often called ?fundamentalism??is one of the most significant problems we face in the world today. Instead, we are calling people into humble dialogue with each other. Rather than demonizing or ostracizing those who disagree with us, we encourage people to adopt an open, listening stance. None of us has the corner on the truth, so we all benefit when we tackle such issues from a variety of perspectives.

Felix: Any challenges or surprises that occurred while the film was being shot?

Kevin: Making a documentary is always tremendously challenging, because unlike a feature film, nothing is scripted. You are always capturing events as they happen, and the outcome is always in question. Even in a sit-down interview situation where you can control a number of variables, the one thing you can?t control is how the subject responds to your questions, so you have to be on your toes at all times recognizing opportunities and capturing them as they occur.

That said, probably the most challenging shoot for us was filming the tenth anniversary memorial of the 9/11 attacks in New York City. Due to terrorist threats, the city was in total lockdown mode, so maneuvering around the city was almost impossible. At one point I thought that entire shoot would be in jeopardy. But somehow we found a way past the bomb-sniffing dogs, armored personnel carriers and machine gun-wielding police and into a spot where we could capture the raw emotion of that day. It was a very powerful experience.

Felix: Most of your films are documentaries. Is there any other genres of film you would be interested in developing?

Kevin: I actually started out like a lot of screenwriters do, dreaming of one day landing a job on a big studio film. So I spent many years chasing that dream. And I still think about it sometimes. But when the top jobs in Hollywood including adapting popular board games into big budget action movies, I have to say my enthusiasm has waned considerably. Also, now that I?ve had a taste of directing?and, more importantly, producing?I think I?d like to pursue opportunities to write and produce some of my own indie features. Possibly direct as well, but I know too many people who are way more qualified for that job than I am. That said, I enjoy making documentaries, so I will continue to do that as well.

Felix: What kind of feedback have you received from HELLBOUND? Have you received any ?threats? from religious radicals?

Kevin: No threats, thankfully, although that possibility has been raised in several interviews. Overall, the reaction has been very positive. Perhaps our most significant negative review came from the bastion of the Protestant Christian establishment, Christianity Today. But that?s expected when you make a movie that questions the status quo. As I?ve traveled across the US doing Q&A screenings in various cities, the reaction has been overwhelmingly positive so far. The same goes for reviews. I?ve been surprised and delighted by positive reviews in Variety, the New York Times, the LA Times, the Huffington Post and even the horror movie web site shockya.com. It?s encouraging to see the film touching a nerve across a vast cross-section of people.

Felix: Being from Abbotsford, BC. When you are not writing or directing, what?s your favorite thing to do in BC?

Kevin: I travel a lot, so when I?m home, I love spending time with my wife Heidi and our four kids. However, I also make hockey a regular part of my weekly schedule. And the ultimate thing for me to do in BC is hike in our lovely mountains during the summer and snowshoe them in the winter. One of my favorite spots is the series of peaks near where the Coquihalla tollbooth used to be.

Felix: If you weren?t making movies, what do you think you would be doing for a career instead?

Kevin: I would be teaching at a university, likely in the area of philosophy or theology. I love big ideas, and I love talking and writing about them even more. So that would have been an ideal alternate career path for me.

Felix: Is there any advice you can give to aspiring directors/screenwriters?

Kevin: Don?t give up. The fall of 2008 when I edited Brad Jersak?s book was a very dark time for me. Two film projects had fallen through one after the other, and literally overnight, I found myself unemployed for the first time in my adult life. I thought my fledgling film career was already over, and I scrambled to find any sort of work to pay the bills. At the same time, I kept putting my name out there, hoping that something would come through. Believe it or not, six months later I found myself involved in not one but five film projects all at once. In fact, I was so busy I thought I was going to lose my mind. So when they say it?s always darkest before the dawn, I have to agree. If I had given up that fall, there?s no way I?d be doing what I am today.

Felix: Thank you for taking the time to speak with me.

HELLBOUND?, is now playing at participating theatres. Check your local listings.

Felix Kay,
Follow Felix on Twitter: @TheFelixKay

Source: http://www.vancitybuzz.com/2012/10/an-interview-with-hellbounds-screenwriter-kevin-miller/

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Fewer qualms for gun-rights groups over Romney now

ST. PAUL, Minn. (AP) ? Gun-rights groups perceive President Barack Obama as a threat to unfettered access to firearms. They once had qualms about Mitt Romney, too.

But times and circumstances have changed for Romney, the GOP presidential nominee now in tune with the National Rifle Association and similar organizations, whose members are motivated voters.

In the tight White House race, every bit of support helps, especially in the most closely contested states and particularly from groups that claim millions of members nationwide.

Romney's prior embrace of weapon-control proposals had put him crossways with the NRA and others. These days, Romney is on their good side by opposing renewal of a federal ban on semiautomatic weapons, additional regulations on gun shows and suggested federal gun registration requirements.

The NRA and some less prominent organizations are spending big money on mailings, radio ads, TV commercials and booths at game fairs to promote the former Massachusetts governor and portray Obama as hostile to gun rights.

Gun groups are an important part of an outdoor enthusiast network that neither side is willing to concede.

There are "Sportsmen for Romney" and "Sportsmen for Obama," all playing to the largely male hook-and-bullet crowd that is protective of recreational passions. Neither candidate is considered an avid outdoorsman, though each has made mention of fishing rods or been photographed casting a line.

Romney and his allies underscore his hands-off stance when it comes to guns, and say he would move to open more public land to hunting. They also promote the bona fides of running mate Paul Ryan, who has a permit for just about every season in Wisconsin, his home state.

Last month, Ryan reminded a gathering of sportsmen in Ohio of the hours he has logged in duck blinds, deer stands, pheasant fields and fishing boats. Then came his critique of Obama: "I wonder, I shudder as a gun owner, seeing his record when he was in the Illinois state Senate, what would he do if he never has to face the voters ever again?"

It's the type of message that resonates with voters such as Stan Glover of Bowerston, Ohio. Glover said Romney's past stands gave him pause, but he's more nervous about Obama.

"The uncertainty of politics in Washington, as regards hunters/gun owner rights, has caused undue fear amongst folks that enjoy the shooting sports," said Glover, a manufacturing plant sales director who plans to vote for Romney.

The Obama campaign emphasizes steps by his administration to promote habitat conservation, set aside land and preserve access to land used for recreation. Supporters point to Obama's "American Great Outdoors Initiative" to coordinate conservation and natural resource efforts in all 50 states, whether it's restoring wetlands in Iowa's duck-rich Prairie Pothole Region or filtering phosphorous harmful to fish and fowl in Grand Lake St. Marys in Ohio.

For Obama, minimizing Romney's apparent advantage among voters who place a premium on outdoors issues is the name of the game.

In Iowa and elsewhere, that task falls to people such as Dick Dearden. He's a Democratic state senator and leader of a group of pro-Obama outdoors enthusiasts working to combat negative portrayals of the incumbent among the shotgun crowd.

"The president is not a threat to people who hunt and fish. He's an asset," Dearden said. "I'm a member of the NRA and they are beginning to more and more embarrass me. I'm a Second Amendment person, but I have not seen anything this president has done for the last four years that has hurt anyone's Second Amendment rights."

Obama's campaign highlights a law he signed in his first year as president that allows people with weapons permits to bring loaded guns into national parks and wildlife refuges. The change drew rebukes from gun-control advocates.

But groups working to defeat Obama sound alarms about his support of reinstating an assault weapons ban if one made it through Congress. They also are stoking fears that the president would use a second term to appoint federal judges with restrictive views toward gun ownership. The Supreme Court has been closely divided in recent gun cases, and the balance could shift if Obama had the chance to pick any new justices.

Romney told the leader of the NRA's lobbying arm in a question-and-answer piece published last month that he would appoint "wise, experienced and restrained judges" and fill his Cabinet with "people who agree that the Second Amendment guarantees a fundamental, individual right."

His own views have evolved from when he ran for the Senate and was governor in Massachusetts. In his failed 1994 Senate campaign he backed a waiting period on gun sales and an assault weapons ban that he said were "not going to make me the hero of the NRA." As governor, he signed a state-level assault weapons ban that he argued was part of a brokered deal between the sides in the gun debate.

In the NRA interview published in September, Romney unequivocally opposed new gun restrictions, including one on semiautomatic weapons. "I do not support any additional laws to restrict the right to keep and bear arms," he said. The group endorsed him in Virginia in early October and has since reserved more than $1.3 million in TV ad time in in Florida, Ohio, Virginia and Wisconsin.

Larry Pratt, executive director of Gun Owners of America, acknowledged some hesitancy about Romney but said gun-rights activists were mollified by his selection of Ryan as a running mate.

"It created a lot more willingness to pull his lever, and at least some enthusiasm," Pratt said. "Ryan is at least one of us."

___

Associated Press writer Mitch Stacy in Columbus, Ohio, contributed to this report.

Source: http://news.yahoo.com/fewer-qualms-gun-rights-groups-over-romney-now-120225900--election.html

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Sunday, October 14, 2012

PA GOP to allow fracking on college campuses (Americablog)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/255213633?client_source=feed&format=rss

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Scientists discover that shape matters in DNA nanoparticle therapy

Saturday, October 13, 2012
This illustration depicts DNA molecules (light green), packaged into nanoparticles by using a polymer with two different segments. One segment (teal) carries a positive charge that binds it to the DNA, and the other (brown) forms a protective coating on the particle surface. By adjusting the solvent surrounding these molecules, the Johns Hopkins and Northwestern researchers were able to control the shape of the nanoparticles. The team?s animal tests showed that a nanoparticle?s shape could dramatically affect how effectively it delivers gene therapy to the cells. The cartoon images in the foreground, obtained though computational modeling, matched closely with the gray background images, which were collected through transmission electron microscopy. Credit: Credits: Wei Qu, Northwestern University, simulation cartoons; Xuan Jiang, Johns Hopkins University, microscopic images

Researchers from Johns Hopkins and Northwestern universities have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference in how well they work in treating cancer and other diseases.

This study, to be published in the Oct. 12 online edition of the journal Advanced Materials, is also noteworthy because this gene therapy technique does not use a virus to carry DNA into cells. Some gene therapy efforts that rely on viruses have posed health risks.

"These nanoparticles could become a safer and more effective delivery vehicle for gene therapy, targeting genetic diseases, cancer and other illnesses that can be treated with gene medicine," said Hai-Quan Mao, an associate professor of materials science and engineering in Johns Hopkins' Whiting School of Engineering.

Mao, co-corresponding author of the Advanced Materials article, has been developing nonviral nanoparticles for gene therapy for a decade. His approach involves compressing healthy snippets of DNA within protective polymer coatings. The particles are designed to deliver their genetic payload only after they have moved through the bloodstream and entered the target cells. Within the cells, the polymer degrades and releases DNA. Using this DNA as a template, the cells can produce functional proteins that combat disease.

A major advance in this work is that Mao and his colleagues reported that they were able to "tune" these particles in three shapes, resembling rods, worms and spheres, which mimic the shapes and sizes of viral particles. "We could observe these shapes in the lab, but we did not fully understand why they assumed these shapes and how to control the process well," Mao said. These questions were important because the DNA delivery system he envisions may require specific, uniform shapes.

To solve this problem, Mao sought help about three years ago from colleagues at Northwestern. While Mao works in a traditional wet lab, the Northwestern researchers are experts in conducting similar experiments with powerful computer models.

Erik Luijten, associate professor of materials science and engineering and of applied mathematics at Northwestern's McCormick School of Engineering and Applied Science and co-corresponding author of the paper, led the computational analysis of the findings to determine why the nanoparticles formed into different shapes.

"Our computer simulations and theoretical model have provided a mechanistic understanding, identifying what is responsible for this shape change," Luijten said. "We now can predict precisely how to choose the nanoparticle components if one wants to obtain a certain shape."

The use of computer models allowed Luijten's team to mimic traditional lab experiments at a far faster pace. These molecular dynamic simulations were performed on Quest, Northwestern's high-performance computing system. The computations were so complex that some of them required 96 computer processors working simultaneously for one month.

In their paper, the researchers also wanted to show the importance of particle shapes in delivering gene therapy. Team members conducted animal tests, all using the same particle materials and the same DNA. The only difference was in the shape of the particles: rods, worms and spheres.

"The worm-shaped particles resulted in 1,600 times more gene expression in the liver cells than the other shapes," Mao said. "This means that producing nanoparticles in this particular shape could be the more efficient way to deliver gene therapy to these cells."

The particle shapes used in this research are formed by packaging the DNA with polymers and exposing them to various dilutions of an organic solvent. DNA's aversion to the solvent, with the help of the team's designed polymer, causes the nanoparticles to contract into a certain shape with a "shield" around the genetic material to protect it from being cleared by immune cells.

###

Northwestern University: http://www.northwestern.edu

Thanks to Northwestern University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/124446/Scientists_discover_that_shape_matters_in_DNA_nanoparticle_therapy_

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Saturday, October 13, 2012

Meningitis outbreak toll: 184 cases in 12 states

An outbreak of fungal meningitis has been linked to steroid shots for back pain. The medication, made by a specialty pharmacy in Massachusetts, has been recalled.

Latest numbers from the Centers for Disease Control and Prevention:

Illnesses: 184

Deaths: 14

States: 12; Florida, Idaho, Indiana, Maryland, Michigan, Minnesota, New Jersey, North Carolina, Ohio, Tennessee, Texas and Virginia.

___

Online:

CDC: http://www.cdc.gov/HAI/outbreaks/meningitis.html

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2012-10-12-Meningitis%20Outbreak-Toll/id-d2d9dda0af0248e0a7bda13374f9083b

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Holiday sales critical for Nokia after weak quarter

HELSINKI (Reuters) - Nokia is expected to report another quarterly loss next week, raising the stakes for its holiday-season sales battle with smartphone rivals Apple and Samsung.

The new top-of-the-range Lumia 820 and 920 smartphones that are vital to Nokia's survival arrive in stores in November, just as people start buying presents for Christmas and other holidays.

Powered by Microsoft's Windows software, they face tough competition from Apple's new iPhone and Samsung's Galaxy SIII.

Analysts said Nokia chief executive Stephen Elop will need to set out a convincing marketing strategy for the Lumia phones, including more details on sales partnerships with mobile network operators, when the company announces its results on October 18.

Once the world's biggest mobile phone maker, Nokia fell behind rivals in smartphones and has racked up more than 3 billion euros in operating losses in the last 18 months.

The Finnish company is pinning its hopes on a partnership with Microsoft to use its Windows software which powers around just 3 percent of the global smartphone market, compared with Google's Android which has cornered two-thirds of the market.

Most analysts have written off Nokia's third quarter as a weak one, without the new Lumia models to help compensate for a drop in sales of older models with running its legacy Symbian software.

"So we're looking at a sort of vacuum in Q3. In addition to that, you have the Symbian volumes coming down very rapidly," said Swedbank analyst Hakan Wranne, who has a "buy" rating on the stock.

On average, analysts forecast Nokia to post an underlying operating loss of 320 million euros ($414 million) from its handset business, according to a Reuters poll.

On a group level the net loss is expected to surge to 780 million euros, or 21 cents per share, from 68 million euros, or 2 cents a share, a year earlier.

WOBBLY START

Nokia's shares have risen more than 45 percent from a year-low of 1.33 euros in July and some analysts say even modest sales success for the new Lumia phones could lift shares higher. They are still down around 70 percent since the Microsoft deal in February 2011.

"If they manage to take say 5 percent of the smartphone market and show just half-decent margins... well then the stock looks attractive at current levels," said Wranne who has a target price of 2.80 euros on Nokia shares.

Nokia's Windows phones are forecast to have made up about 2 percent of global smartphone sales in the third quarter.

If Nokia fails to show Lumia volumes picking up by early next year, many investors and analysts have said the company may need to change its strategy -- as well as its leader.

Of 30 analysts surveyed by Reuters, nine had a "sell" rating on the stock and seven had a "buy." The rest recommended a "hold".

The Lumia phones had a wobbly launch in September, disappointing investors who complained about a lack of detail on pricing and partnerships with the network operators that distribute and subsidize phones.

The company has since announced a partnership with AT&T in the United States and some prices in Europe, but analysts said Elop needs to convince investors it has the right partnerships and sales incentives in place to promote Lumia phones.

"It will be a tough proposition," said James Crawshaw, analyst at S&P Capital IQ Equity, who rates the stock a "hold".

Another concern is that Nokia may run out of cash. Its cash position is forecast to fall to 3.4 billion euros at the end of the third quarter from 4.2 billion three months earlier.

Nokia has been cutting spending and selling assets such as its Vertu luxury handset division. It is also considering selling and leasing back its waterfront headquarters in Espoo, a short drive from Helsinki.

Spreads on Nokia's bonds show many investors are wary. Five-year credit default swaps on Nokia's debt have climbed to 1,068 points, implying a probability of default around 61 percent.

($1=0.7726 euros)

(Additional reporting by Tarmo Virki; Editing by Erica Billingham)

Source: http://news.yahoo.com/holiday-sales-critical-nokia-weak-quarter-134706260--finance.html

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